SELECTED REFERENCES for
Enhanced ECG Analyses

including SuperScores, HFQRS, QTV, TWM, and others...

  1. Schlegel TT, Arenare B, Greco EC, DePalma JL, Starc V, Nunez T, Medina R, Jugo DJ, Rahman MA, Delgado R. Construction and Use of Resting 12-Lead High Fidelity ECG “SuperScores” in Screening for Heart Disease.
    Computers in Cardiology Annual Meeting 2007.

  2. Starc V, Schlegel TT, Arenare B, Greco EC, DePalma JL, Nunez T, Medina R, Jugo DJ, Rahman MA, Delgado R. Multi-Channel System for Beat to Beat QT Interval Variability and Its Use in Screening for Coronary Artery Disease and Cardiomyopathy. Computers in Cardiology Annual Meeting 2007.

  3. Trägårdh E, Schlegel TT. High-frequency QRS electrocardiogram. Review article.
    Clinical Physiology and Functional Imaging. March 2007.

  4. Schlegel TT, Medina R, Jugo D, Nuñez T, Borrego A, Arrellano A, Arenare B, DePalma J, Greco EC, Starc V. Cardiac Repolarization Abnormalities and Potential Evidence for Loss of Cardiac Sodium Currents on ECGs of Patients with Chagas’ Heart Disease. ISCE 2007  

  5. Rahman MA, Delgado R, Poulin G, Starc V, Arenare B, Swafford J, Schlegel TT.
    A Resting Electrocardiography “SuperScore” for Heart Disease Screening.
    33rd International Congress on Electrocardiology, June 2006.

  6. Trägårdh E, Pettersson J, Wagner GS, Pahlm O. Reduced high-frequency QRS components in electrocardiogram leads facing an area of the heart with intraventricular conduction delay due to bundle branch block. J Electrocardiol. 2007 Mar;40(2):127-132.  

  7. Starc V, Schlegel TT. Real-time multichannel system for beat-to-beat QT interval variability. J Electrocardiol. 2006 Oct;39(4):358-367.  

  8. Trägårdh E, Pahlm O, Heden B, Sornmo L, Tagil K, Wagner GS, Pettersson J.
    Serial changes in the high-frequency ECG during the first year following acute myocardial infarction.
    Clin Physiol Funct Imaging. 2006 Sep;26(5):296-300.   
    full text


  9. Scott NP, Greco EC, Schlegel TT. Effect of direct current offset on the T-wave residuum parameter, 12 September 2006 J Electrocardiol. 2006 Mar;39(4):S131. 

  10. Rahman MA, Gedevanishvili A, Birnbaum Y, Sarmiento L, Sattam W, Kulecz WB Schlegel TT. High-frequency QRS electrocardiogram predicts perfusion defects during myocardial perfusion imaging.   J Electrocardiol. 2006 Jan;39(1):73-81.   text/pdf 

  11. Douglas PK, Batdorf NJ, Evans RT, Feiveson AH, Arenare B, Schlegel TT. Temporal and Postural variation of 12-lead high-frequency QRS electrocardiographic signals in asymptomatic patients.   J Electrocardiol. 2006 Jul;39(3):259-65.   text/pdf 

  12. Batdorf BH, Feiveson AH, Schlegel TT. The effect of signal averaging on the reproducibility and reliability of measures of T-wave morphology.  
    J Electrocardiol. 2006 Jul;39(3):266-70.
       text/pdf 


  13. Rahman MA, Delgado R, Poulin G, Starc V, Arenare B, Swafford J, Schlegel TT.    A Resting Electrocardiography SuperScore for Heart Disease Screening.    The International Society of Electrocardiology, 33rd Int'l Congress, June 2006.    poster 

  14. Schlegel TT, Arenare B, Poulin G, Moser DR, Delgado R.  High Frequency QRS ECG Accurately Detects Cardiomyopathy.  32nd Congress Intl Soc of Electrocardiology. 2005.   abstract

  15. Rahman AM, Gedevanishvili A, Sarmiento L, Sattam WB, Schlegel TT. High frequency QRS electrocardiogram predicts ischemic effects during perfusion imaging. J Electrocardiol. 2005.   poster

  16. Vrtovec B, Sinkovec M, Starc V, Radovancevic B, Schlegel TT. Coronary Artery Disease Alters Ventricular Repolarization Dynamics in Type 2 Diabetes. Pacing Clin Electrophysiol. 2005;28:S178-181.   abstract

  17. Schlegel TT, Kulecz WB, DePalma JL, Feiveson AH, Wilson JS, Rahman MA, Bungo MW. Real-time 12-lead high frequency QRS electrocardiography for enhanced detection of myocardial ischemia and coronary artery disease. Mayo Clin Proc. 2004 Mar;79(3):339-50.    full text   pdf

  18. Rahman AM, Gedevanishvili A, Bungo MW, Vijayakumar V, Chamoun A, Birnbaum Y, Schlegel TT. Non-invasive detection of coronary artery disease by a newly developed high-frequency QRS electrocardiogram. Physiol Meas. 2004 Aug;25(4):957-65.    abstract   (pdf) 

  19. Delgado RM, Poulin GV, Vrtovec B, Eastwood C, Radovancevic B, Franklin W, Kar B, Schlegel TT. The Utility of High Frequency QRS Electrocardiogram in the Diagnosis of Cardiomyopathy.  Am College of Cardiology, Annual Meeting 2004.    abstract 

  20. Batdorf NJ, Feiveson AH and Schlegel TT. Month-to-month and year-to-year reproducibility of high frequency QRS ECG signals. J Electrocardiol. 2004 Oct;37(4):289-96.    text/pdf 

  21. Garvey JL, Schlegel TT, DeSilva SJ, Marx JA. High-frequency ECG in the identification of acute coronary syndromes in emergency department patients with chest pain. Ann Emer Med. 2003;42(4):S5.  

  22. Schlegel TT, Arenare B, Kulecz, Greco EC.  The electrocardiogram of the 21st century - enabling it together. NASA Bioengineering 2003.   presentation 

  23. Schlegel TT, Gedevanishvili A, Ahman N, Rahman A, Bungo MW. Newly Developed high frequency QRS electrocardiograph in the detection of coronary disease. American College of Cardiology, Annual Meeting 2003.  abstract 

  24. Spackman TN, Abel MD, Schlegel TT. Changes in 12-lead high frequency QRS electrocardiography following induction of anesthesia in healthy individuals. Anesthesiology 2002; 96:A495

  25. Schlegel TT, Arenare B, Kulecz WB, DePalma JL. Multichannel high frequency QRS electrocardiograph for early diagnosis of myocardial ischemia and infarction. Frontiers of Cardiology    Best Research Award 2002 Annual Session.

  26. Vrtovec B, Starc V, Starc R. Beat-to-beat QT interval variability in coronary patients. J Electrocardiol. 2000 Apr;33(2):119-25.


  27. Trägårdh E, Pahlm O, Wagner GS and Pettersson J. Reduced high-frequency QRS components in patients with ischemic heart disease compared to normal subjects. J Electrocardiol. 2004 Jul;37(3):157-62.    full text  pdf

  28. Beker A, Abbo A, Abboud S, Strasberg B. High frequency mid-QRS potentials during treadmill ergometry in cases of inconclusive ST-based diagnosis. J Electrocardiol. 2004 Oct;37(4)Suppl:78-79.    abstract

  29. Ringborn M, Pahlm O, Wagner GS, Warren SG, Pettersson J. The absence of high-frequency QRS changes in the presence of standard electrocardiographic QRS changes of old myocardial infarction. Am Heart J. 2001;141:573-9.

  30. Pettersson J, Pahlm O, Carro E, et al. Changes in high-frequency QRS components are more sensitive than ST-segment deviation for detecting acute coronary artery occlusion. J Am Coll Cardiol. 2000;36:1827-34.

  31. Pettersson J, Carro E, Edenbrandt L, et al. Spatial, individual, and temporal variation of the high-frequency QRS amplitudes in the 12 standard electrocardiographic leads. Am Heart J. 2000;139:352-8.

  32. Maehara K, Kokubun T, Awano N, et al. Detection of abnormal high-frequency components in the QRS complex by the wavelet transform in patients with idiopathic dilated cardiomyopathy. Jpn Circ J. 1999;63:25-32.

  33. Selvester RH. A call to concerted action for change. The recording, display, and reporting of the routine electrocardiogram. J Electrocardiol. 1998;31:367-70.

  34. Abboud S, Cohen RJ, Selwyn A, Ganz P, Sadeh D, Friedman PL. Detection of transient myocardial ischemia by computer analysis of standard and signal-averaged high-frequency electrocardiograms in patients undergoing percutaneous transluminal coronary angioplasty. Circulation. 1997;76:585-96.

  35. Beker A, Pinchas A, Erel J, Abboud S. Analysis of high frequency QRS potential during exercise testing in patients with coronary artery disease and in healthy subjects. Pacing Clin Electrophysiol. 1996;19:2040-50.

  36. Seegobin RD, Mohamed SA. Sex differences and frequency content of the Frank lead signal-averaged ECG in a normal population.J Electrocardiol. 1996;29:105-9.

  37. Seegobin RD, Mohamed SA, Ropchan G, Pym J. Frequency content and sex difference of the Frank lead signal-averaged ECG in a population with significant coronary artery disease. Comparison with concurrent 12-lead ECG morphology. J Electrocardiol. 1995;28:228-33.

  38. Xue Q, Reddy BR, Aversano T. Analysis of high-frequency signal-averaged ECG measurements. J Electrocardiol. 1995;28:239-45.

  39. Aversano T, Rudikoff B, Washington A, Traill S, Coombs V, Raqueno J. High frequency QRS electrocardiography in the detection of reperfusion following thrombolytic therapy. Clin Cardiol. 1994;17:175-82.

  40. Abboud S. High-frequency electrocardiogram analysis of the entire QRS in the diagnosis and assessment of coronary artery disease. Prog Cardiovasc Dis. 1993;35:311-28.

  41. Berkalp B, Baykal E, Caglar N, Erol C, Akgun G, Gurel T. Analysis of high frequency QRS potentials observed during acute myocardial infarction. Int J Cardiol. 1993;42:147-53.

  42. Abboud S, Berenfeld O, Sadeh D. Simulation of high-resolution QRS complex using a ventricular model with a fractal conduction system. Effects of ischemia on high-frequency QRS potentials. Circ Res. 1991;68:1751-60.

  43. Mor-Avi V, Akselrod S. Spectral analysis of canine epicardial electrogram. Short-term variations in the frequency content induced by myocardial ischemia. Circ Res. 1990;66:1681-91.

  44. Mor-Avi V, Akselrod S. Some aspects of the wideband recording of the electrocardiogram. Clin Cardiol. 1990;13:120-6.

  45. Abboud S, Cohen RJ, Sadeh D. A spectral analysis of the high frequency QRS potentials observed during acute myocardial ischemia in dogs. Int J Cardiol. 1990;26:285-90.

  46. Abboud S, Smith JM, Shargorodsky B, Laniado S, Sadeh D, Cohen RJ. High frequency electrocardiography of three orthogonal leads in dogs during a coronary artery occlusion. Pacing Clin Electrophysiol. 1989;12:574-81.

  47. Akselrod S, Mor-Avi V, Oz O, David D. Effect of localized surface cooling of the heart muscle on the high-frequency content of ECG waveforms in dogs. Clin Cardiol. 1988;11:112-8.

  48. Abboud S. Subtle alterations in the high-frequency QRS potentials during myocardial ischemia in dogs. Comput Biomed Res. 1987;20:384-95.

  49. Abboud S, Belhassen B, Miller HI, Sadeh D, Laniado S. High frequency electrocardiography using an advanced method of signal averaging for non-invasive detection of coronary artery disease in patients with normal conventional electrocardiogram. J Electrocardiol. 1986;19:371-80.

  50. Goldberger AL, Bhargava V, Froelicher V, Covell J. Effect of myocardial infarction on high-frequency QRS potentials. Circulation. 1981;64:34-42.